Effect of fluvastatin therapy on coronary flow reserve in patients with hypercholesterolemia

Am J Cardiol. 2004 Jun 1;93(11):1419-21, A10. doi: 10.1016/j.amjcard.2004.02.046.

Abstract

Coronary flow reserve was evaluated using transthoracic Doppler echocardiography before and after 3 months of fluvastatin therapy in patients with hypercholesterolemia. Coronary flow reserve increased significantly after lipid-lowering therapy, and coronary microcirculation was improved in patients with hypercholesterolemia.

MeSH terms

  • Coronary Circulation / physiology*
  • Echocardiography, Doppler / methods
  • Fatty Acids, Monounsaturated / therapeutic use*
  • Female
  • Fluvastatin
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Hypercholesterolemia / diagnostic imaging
  • Hypercholesterolemia / drug therapy*
  • Hypercholesterolemia / physiopathology
  • Indoles / therapeutic use*
  • Male
  • Middle Aged
  • Time Factors

Substances

  • Fatty Acids, Monounsaturated
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Indoles
  • Fluvastatin