Abstract
The diagnostic applicability of the Clonorchis sinensis recombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Protozoan / immunology
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Antigens, Protozoan / immunology*
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Clonorchiasis / diagnosis*
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Clonorchiasis / immunology
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Clonorchis sinensis / immunology
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Cross Reactions / immunology
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Electrophoresis, Polyacrylamide Gel
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Enzyme-Linked Immunosorbent Assay
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Humans
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Immunoblotting
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Parasitic Diseases / diagnosis
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Parasitic Diseases / immunology
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Recombinant Proteins / immunology*
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Sensitivity and Specificity
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Serologic Tests* / methods
Substances
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Antibodies, Protozoan
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Antigens, Protozoan
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Recombinant Proteins