The Goodman-Kruskal coefficient and its applications in genetic diagnosis of cancer

IEEE Trans Biomed Eng. 2004 Jul;51(7):1095-102. doi: 10.1109/TBME.2004.827267.

Abstract

Increasing interest in new pattern recognition methods has been motivated by bioinformatics research. The analysis of gene expression data originated from microarrays constitutes an important application area for classification algorithms and illustrates the need for identifying important predictors. We show that the Goodman-Kruskal coefficient can be used for constructing minimal classifiers for tabular data, and we give an algorithm that can construct such classifiers.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Algorithms*
  • Cluster Analysis
  • Diagnosis, Computer-Assisted / methods*
  • Genetic Testing / methods
  • Humans
  • Neoplasms / diagnosis*
  • Neoplasms / genetics*
  • Oligonucleotide Array Sequence Analysis / methods*
  • Pattern Recognition, Automated
  • Reproducibility of Results
  • Sensitivity and Specificity