Antiphospholipid and antisynthetase syndrome in a patient with polymyositis-rheumatoid arthritis overlap

Clin Rheumatol. 2004 Aug;23(4):371-2. doi: 10.1007/s10067-004-0903-x. Epub 2004 Apr 14.

Abstract

Idiopathic inflammatory myopathies, mainly polymyositis (PM) may occur in the course of several autoimmune diseases. The overlapping forms of myositis, when the patient also meets the criteria for rheumatoid arthritis (RA), affect 3%-5% of myositis patients [1]. To the best of our knowledge this is the first report on the overlapping form of RA, antiphospholipid syndrome (APS) and the serological subgroup of PM, the antisynthetase syndrome (ASS).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Antinuclear / blood
  • Antiphospholipid Syndrome / complications*
  • Antiphospholipid Syndrome / drug therapy
  • Antiphospholipid Syndrome / pathology
  • Arthritis, Rheumatoid / complications*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / pathology
  • Cyclosporine / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Hand / pathology
  • Humans
  • Ligases / immunology*
  • Lung / diagnostic imaging
  • Lung Diseases, Interstitial / complications*
  • Lung Diseases, Interstitial / diagnostic imaging
  • Lung Diseases, Interstitial / drug therapy
  • Magnetic Resonance Imaging
  • Polymyositis / complications*
  • Polymyositis / drug therapy
  • Polymyositis / pathology
  • Remission Induction
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antibodies, Antinuclear
  • Glucocorticoids
  • Jo-1 antibody
  • Cyclosporine
  • Ligases