Babies of 17 HBsAg positive mothers were passively and actively immunized with HBIG and HBV vaccine. Seven infants born from HBsAg (+) mothers were not immunized with their families decisions and used as control group. 24 infants were followed for 12-18 months. 76.4% of immunized babies were anti-HBs positive at 12 months. None of the babies who were not immunized were HBsAg positive at 12 months.