Abstract
The immune response to heat shock protein A (HspA) in Helicobacter pylori-positive adults increases with age in developed countries. This response has not been studied with children or in developing countries (G. I. Pérez-Pérez, J. M. Thiberge, A. Labigne, and M. J. Blaser, J. Infect. Dis. 174:1046-1050, 1996). As determined by using a specific enzyme-linked immunosorbent assay, HspA seropositivity among 592 individuals in Mexico was <10% in children and increased to >40% in adults.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Age Factors
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Antibody Formation*
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Bacterial Proteins / immunology*
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Child
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Child, Preschool
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Heat-Shock Proteins / immunology*
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Helicobacter Infections / diagnosis
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Helicobacter Infections / epidemiology
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Helicobacter Infections / immunology*
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Helicobacter pylori*
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Humans
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Infant
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Infant, Newborn
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Matched-Pair Analysis
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Mexico
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Middle Aged
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Serologic Tests
Substances
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Bacterial Proteins
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Heat-Shock Proteins
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HspA protein, bacteria