23-oxa-analogues of OSW-1: efficient synthesis and extremely potent antitumor activity

Angew Chem Int Ed Engl. 2004 Aug 20;43(33):4324-7. doi: 10.1002/anie.200454237.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemical synthesis*
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Cholestenones / chemical synthesis*
  • Cholestenones / chemistry
  • Cholestenones / pharmacology
  • Drug Screening Assays, Antitumor
  • Humans
  • Inhibitory Concentration 50
  • Ornithogalum / chemistry
  • Saponins / chemical synthesis*
  • Saponins / chemistry
  • Saponins / pharmacology
  • Structure-Activity Relationship

Substances

  • Antineoplastic Agents, Phytogenic
  • Cholestenones
  • Saponins
  • OSW 1