Topical imiquimod treatment of lentigo maligna: clinical and histologic evaluation

J Am Acad Dermatol. 2004 Oct;51(4):635-9. doi: 10.1016/j.jaad.2004.05.004.

Abstract

We have treated extensive lentigo maligna in two elderly patients with Imiquimod 5% (Aldara). It was applied 3 times weekly, for 3 to 5 months. Clinical and histological remission was observed over 13 months of follow-up care. Tolerance was good. We suggest that topical imiquimod could be an interesting therapeutic alternative.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Aminoquinolines / administration & dosage*
  • Antineoplastic Agents / administration & dosage*
  • Biopsy
  • Drug Administration Schedule
  • Female
  • Humans
  • Hutchinson's Melanotic Freckle / drug therapy*
  • Hutchinson's Melanotic Freckle / pathology*
  • Imiquimod
  • Male
  • Skin / pathology
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology*
  • Treatment Outcome

Substances

  • Aminoquinolines
  • Antineoplastic Agents
  • Imiquimod