The generation of cloned Drosophila melanogaster

Genetics. 2005 Feb;169(2):1165-7. doi: 10.1534/genetics.104.035113. Epub 2004 Oct 16.

Abstract

We report here the first successful use of embryonic nuclear transfer to create viable adult Drosophila melanogaster clones. Given the generation time, cost effectiveness, and relative ease of embryonic nuclear transplant in Drosophila, this method can provide an opportunity to further study the constraints on development imposed by transplanting determined or differentiated nuclei.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Culture Techniques
  • Clone Cells
  • Cloning, Organism / economics
  • Cloning, Organism / methods*
  • DNA / analysis
  • DNA, Mitochondrial / analysis
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / genetics
  • Embryo, Nonmammalian / cytology
  • Genetic Markers
  • Nuclear Transfer Techniques*
  • Transgenes

Substances

  • DNA, Mitochondrial
  • Genetic Markers
  • DNA