Assessing clonality of Vibrio cholerae Inaba isolates by characterization of nonsense mutations in wbeT

J Med Microbiol. 2004 Nov;53(Pt 11):1105-1107. doi: 10.1099/jmm.0.45744-0.

Abstract

The transferase gene wbeT of six clinical isolates of Vibrio cholerae O1 biotype El Tor was analysed. Two unique mutations were identified in the wbeT gene of three Inaba isolates. Due to their random nature, mutations in wbeT can be used to determine the clonal origin of clinical Inaba isolates.

MeSH terms

  • Bacterial Proteins / genetics*
  • Cholera / microbiology*
  • Codon, Nonsense*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / isolation & purification
  • Genes, Bacterial*
  • Humans
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Vibrio cholerae / classification
  • Vibrio cholerae / genetics*
  • Vibrio cholerae / isolation & purification

Substances

  • Bacterial Proteins
  • Codon, Nonsense
  • DNA, Bacterial
  • RfbT protein, Vibrio cholerae

Associated data

  • GENBANK/AY458621
  • GENBANK/AY458622
  • GENBANK/AY458623
  • GENBANK/AY458624
  • GENBANK/AY458625
  • GENBANK/AY458626