Antibiotic susceptibility in neonatal invasive isolates of Streptococcus agalactiae in a 2-year nationwide surveillance study in Germany

Antimicrob Agents Chemother. 2004 Nov;48(11):4444-6. doi: 10.1128/AAC.48.11.4444-4446.2004.

Abstract

The antimicrobial susceptibility of 296 invasive neonatal group B streptococcus isolates from a nationwide 2-year surveillance study in Germany was investigated. All isolates were susceptible to beta-lactams, linezolid, quinupristin-dalfopristin, and vancomycin. Erythromycin and clindamycin resistance was found in 10.1 and 5.7%, respectively. The ermB, ermTR, or mefA gene was detected in all but one of the erythromycin-resistant isolates.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics
  • Drug Resistance, Bacterial
  • Genes, Bacterial
  • Germany / epidemiology
  • Humans
  • Infant, Newborn
  • Membrane Proteins / genetics
  • Methyltransferases / genetics
  • Microbial Sensitivity Tests
  • Population Surveillance
  • Reverse Transcriptase Polymerase Chain Reaction
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / microbiology*
  • Streptococcus agalactiae / drug effects*
  • Streptococcus agalactiae / genetics

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • MefA protein, Streptococcus
  • Membrane Proteins
  • ErmTR protein, bacteria
  • Methyltransferases
  • ErmA protein, Bacteria