Abstract
The antimicrobial susceptibility of 296 invasive neonatal group B streptococcus isolates from a nationwide 2-year surveillance study in Germany was investigated. All isolates were susceptible to beta-lactams, linezolid, quinupristin-dalfopristin, and vancomycin. Erythromycin and clindamycin resistance was found in 10.1 and 5.7%, respectively. The ermB, ermTR, or mefA gene was detected in all but one of the erythromycin-resistant isolates.
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics
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Drug Resistance, Bacterial
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Genes, Bacterial
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Germany / epidemiology
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Humans
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Infant, Newborn
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Membrane Proteins / genetics
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Methyltransferases / genetics
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Microbial Sensitivity Tests
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Population Surveillance
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Reverse Transcriptase Polymerase Chain Reaction
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Streptococcal Infections / epidemiology
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Streptococcal Infections / microbiology*
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Streptococcus agalactiae / drug effects*
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Streptococcus agalactiae / genetics
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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MefA protein, Streptococcus
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Membrane Proteins
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ErmTR protein, bacteria
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Methyltransferases
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ErmA protein, Bacteria