Accumulation of iron oxide particles around liver metastases during MR imaging

Gastrointest Radiol. 1992 Spring;17(2):173-4. doi: 10.1007/BF01888539.

Abstract

The histologic nature of the bright ring ("peritumoral edema") around some liver metastases on T2-weighted magnetic resonance (MR) images is controversial. In the case reported, particles of the iron oxide contrast agent AMI-25 are retained in the peritumoral zone of a colon cancer metastasis, causing the bright ring to disappear. The location of iron particles in resected specimens could be used systematically to study peritumoral edema.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / secondary*
  • Colorectal Neoplasms / pathology
  • Contrast Media*
  • Dextrans
  • Ferrosoferric Oxide
  • Humans
  • Iron*
  • Liver / pathology
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / secondary*
  • Magnetic Resonance Imaging*
  • Magnetite Nanoparticles
  • Male
  • Middle Aged
  • Oxides*

Substances

  • Contrast Media
  • Dextrans
  • Magnetite Nanoparticles
  • Oxides
  • Iron
  • ferumoxides
  • Ferrosoferric Oxide