The health care staff is potentially more exposed to contract infectious diseases at work. This risk becomes true if the DPI are not utilized and the operators don't work according to the standard protocol, and, with regard to the health care students, they begin their clinical training without the right knowledges. To verify the adequacy of knowledges and the consequent behaviours we effected a study among the students at first year of the D. U. for nurses in the University of L'Aquila, through a questionnaire. It came out many gaps of knowledges about the standard practice and about the Universal Precautions in about 20% of the interviewed.