Report on the discovery of a novel 3-hydroxy oxylipin cascade in the yeast Saccharomycopsis synnaedendra

Olihile M Sebolai; Johan L F Kock; Carolina H Pohl; Piet J Botes; Santosh Nigam

doi:10.1016/j.prostaglandins.2004.07.002

Report on the discovery of a novel 3-hydroxy oxylipin cascade in the yeast Saccharomycopsis synnaedendra

Prostaglandins Other Lipid Mediat. 2004 Oct;74(1-4):139-46. doi: 10.1016/j.prostaglandins.2004.07.002.

Authors

Olihile M Sebolai¹, Johan L F Kock, Carolina H Pohl, Piet J Botes, Santosh Nigam

Affiliation

¹ Department of Microbial, Biochemical and Food Biotechnology, faculty of Natural and Agricultural Sciences, University of the Free State, UNESCO MIRCEN: Industrial Biotechnology, Bloemfontein 9300, South Africa.

PMID: 15560122
DOI: 10.1016/j.prostaglandins.2004.07.002

Abstract

A novel cascade of 3-hydroxy fatty acids was discovered in the yeast Saccharomycopsis synnaedendra. The cascade, probably derived from incomplete beta-oxidation, comprises both even and uneven carbon numbered as well as saturated and unsaturated 3-hydroxy oxylipins. This yeast may now be used as model to further study the metabolism of these compounds as well as their biotechnological production.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Ascomycota / metabolism*
Fatty Acids / metabolism*
Gas Chromatography-Mass Spectrometry
Spectrometry, Mass, Electrospray Ionization

Substances

Fatty Acids