Clinical protocol. Phase I trial to evaluate the safety of H5.020CMV.PDGF-b and limb compression bandage for the treatment of venous leg ulcer: trial A

Hum Gene Ther. 2004 Oct;15(10):1003-19. doi: 10.1089/hum.2004.15.1003.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I

MeSH terms

  • Adenoviridae / genetics
  • Animals
  • Bandages*
  • Becaplermin
  • Clinical Trials as Topic
  • Genetic Therapy / methods*
  • Genetic Vectors
  • Humans
  • Inflammation
  • Leg / pathology
  • Leg Ulcer / etiology
  • Leg Ulcer / therapy*
  • Platelet-Derived Growth Factor / genetics
  • Platelet-Derived Growth Factor / metabolism
  • Pressure
  • Prospective Studies
  • Proto-Oncogene Proteins c-sis
  • Rabbits
  • Receptor, Platelet-Derived Growth Factor beta / metabolism
  • Varicose Ulcer / pathology
  • Varicose Ulcer / therapy*
  • Wound Healing*

Substances

  • Platelet-Derived Growth Factor
  • Proto-Oncogene Proteins c-sis
  • Becaplermin
  • Receptor, Platelet-Derived Growth Factor beta