Clinicopathological study of bronchogenic carcinoma

Respirology. 2004 Nov;9(4):557-60. doi: 10.1111/j.1440-1843.2004.00600.x.

Abstract

Objective: The present study was undertaken to explore the clinicopathological profile of bronchogenic carcinoma.

Methodology: Four hundred consecutive patients with histopathologically proven bronchogenic carcinoma, hospitalized between 1985 and 1999 at a large teaching and tertiary care referral hospital at King George's Medical University in Lucknow, India, were analysed.

Results: The average age of the bronchogenic carcinoma patients was 57 years; 9.8% of patients were less than 40 years of age; the ratio of male to female patients was 4.3:1.0; 71% were smokers; and 87% of the smoking patients were bidi smokers. The most common histological type was squamous-cell carcinoma (46.5%), followed by adenocarcinoma (18.5%) and small-cell carcinoma (18.2%). The majority of patients (74.2%) were diagnosed in the late stages of the disease (IIIb and IV).

Conclusion: Bidi smoking is an important contributory factor in the development of bronchogenic carcinoma in India, and approximately 25% of patients with bronchogenic carcinoma are non-smokers.

MeSH terms

  • Adenocarcinoma / epidemiology
  • Adult
  • Age Distribution
  • Carcinoma, Bronchogenic / diagnosis*
  • Carcinoma, Bronchogenic / epidemiology*
  • Carcinoma, Small Cell / epidemiology
  • Carcinoma, Squamous Cell / epidemiology
  • Comorbidity
  • Diagnostic Errors / statistics & numerical data
  • Diagnostic Techniques, Respiratory System / statistics & numerical data
  • Female
  • Humans
  • India / epidemiology
  • Male
  • Middle Aged
  • Sex Distribution
  • Smoking / epidemiology