Epidemiology and aetiology of epilepsy in sub-Saharan Africa

Lancet Neurol. 2005 Jan;4(1):21-31. doi: 10.1016/S1474-4422(04)00963-9.

Abstract

Data on the incidence of and prognosis for epilepsy in sub-Saharan Africa are scarce, but prevalence data show that epilepsy is two or three times more common than in industrialised countries in non-tropical areas. The high prevalence of epilepsy and low life expectancy indicate that incidence is high. Relative contributions of each cause of epilepsy are difficult to determine. Only a few case-control studies have been done in sub-Saharan Africa. Infections, in particular cysticercosis in its endemic areas, cause most cases of epilepsy. The implementation of studies to accurately determine the causes of epilepsy in sub-Saharan Africa is urgently required. Such studies will help to lower the incidence of epilepsy in this region and better understand the aetiology of epilepsy in other areas.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Africa South of the Sahara / epidemiology
  • Brain Neoplasms / complications
  • Case-Control Studies
  • Central Nervous System Infections / complications
  • Cerebrovascular Disorders / complications
  • Craniocerebral Trauma / complications
  • Epilepsy / epidemiology*
  • Epilepsy / etiology*
  • Epilepsy / genetics
  • Epilepsy / microbiology
  • Female
  • Humans
  • Incidence
  • Male
  • Prevalence
  • Prognosis
  • Risk Factors
  • Seizures, Febrile / complications