Abstract
The authors evaluated four patients with schizencephaly who underwent subtraction ictal SPECT coregistered to MRI (SISCOM) prior to epilepsy surgery. Three patients had a SISCOM alteration that was concordant with the epileptic brain tissue. Two of these patients were rendered seizure-free and one individual experienced a significant reduction in seizures. The patient with an indeterminate SISCOM had an unfavorable outcome. SISCOM is useful in evaluating patients with schizencephaly for epilepsy surgery.
MeSH terms
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Adolescent
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Adult
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Cerebral Cortex / abnormalities*
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Cerebral Cortex / blood supply
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Cerebral Cortex / diagnostic imaging
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Cerebral Cortex / surgery
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Cerebrovascular Circulation
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Epilepsies, Partial / diagnostic imaging
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Epilepsies, Partial / etiology
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Epilepsies, Partial / surgery*
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Humans
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Learning Disabilities / diagnostic imaging
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Learning Disabilities / etiology
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Magnetic Resonance Imaging
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Memory Disorders / diagnostic imaging
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Memory Disorders / etiology
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Paresis / diagnostic imaging
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Paresis / etiology
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Postoperative Period
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Preoperative Care
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Tomography, Emission-Computed, Single-Photon*
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Treatment Outcome