A treatment using STI571 for jejunal gastrointestinal stromal tumor (GIST) accompanied with liver metastasis and peritoneal dissemination

Intern Med. 2004 Dec;43(12):1151-6. doi: 10.2169/internalmedicine.43.1151.

Abstract

A 64-year-old man with a chief complaint of melena visited our emergency outpatient clinic. After several examinations, he was diagnosed as a gastrointestinal stromal tumor (GIST) with liver metastasis. Surgical resection of the jejunal lesion and postoperative adjuvant therapy with STI571 for one year was performed. Due to recent immunohistological studies and introduction of STI571, the diagnosis, treatment, and prognosis of GIST are about to change profoundly. Further accumulation of cases is necessary to investigate the diagnosis, treatment, and prognosis of GIST.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Benzamides
  • Gastrointestinal Stromal Tumors / diagnostic imaging
  • Gastrointestinal Stromal Tumors / drug therapy*
  • Gastrointestinal Stromal Tumors / secondary
  • Humans
  • Imatinib Mesylate
  • Jejunal Neoplasms / diagnostic imaging
  • Jejunal Neoplasms / drug therapy*
  • Jejunal Neoplasms / pathology
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Peritoneal Neoplasms / diagnostic imaging
  • Peritoneal Neoplasms / secondary*
  • Piperazines / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents
  • Benzamides
  • Piperazines
  • Pyrimidines
  • Imatinib Mesylate