Medicine. Treating neurodegenerative diseases with antibiotics

Science. 2005 Jan 21;307(5708):361-2. doi: 10.1126/science.1109027.
No abstract available

MeSH terms

  • Amyotrophic Lateral Sclerosis / drug therapy*
  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Brain / metabolism
  • Ceftriaxone / pharmacology
  • Ceftriaxone / therapeutic use*
  • Clinical Trials as Topic
  • Drug Evaluation, Preclinical
  • Excitatory Amino Acid Transporter 2 / genetics
  • Excitatory Amino Acid Transporter 2 / metabolism
  • Glutamic Acid / metabolism
  • Humans
  • Mice
  • Motor Neurons / physiology
  • Neurodegenerative Diseases / drug therapy*
  • Spinal Cord / metabolism
  • Synapses / physiology
  • Synaptic Transmission
  • beta-Lactams / pharmacology
  • beta-Lactams / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Excitatory Amino Acid Transporter 2
  • beta-Lactams
  • Glutamic Acid
  • Ceftriaxone