Cervico-medullary desmoplastic infantile ganglioglioma: an unusual case with diffuse leptomeningeal dissemination at diagnosis

Pediatr Blood Cancer. 2005 Dec;45(7):986-90. doi: 10.1002/pbc.20325.

Abstract

Desmoplastic infantile ganglioglioma (DIG) is a rare intracranial tumor affecting newborns and infants, and generally arising in the supratentorial region. We report a case of an unusual DIG, arising at the cervico-medullary junction, with diffuse leptomeningeal seeding at diagnosis that was treated with chemotherapy (CT) and delayed partial surgery. The case we describe demonstrates that DIG can occur in the subtentorial region and can show leptomeningeal dissemination like other low-grade gliomas.

Publication types

  • Case Reports

MeSH terms

  • Ganglioglioma / diagnostic imaging*
  • Ganglioglioma / pathology*
  • Ganglioglioma / therapy
  • Humans
  • Infant
  • Magnetic Resonance Imaging* / methods
  • Male
  • Meningeal Neoplasms / diagnostic imaging*
  • Meningeal Neoplasms / pathology*
  • Meningeal Neoplasms / therapy
  • Radiography