Multiple bilateral choroidal metastatic tumors from a small-cell neuroendocrine carcinoma of unknown primary site

Eur J Ophthalmol. 2005 Jan-Feb;15(1):148-52. doi: 10.1177/112067210501500126.

Abstract

Purpose: To report one case of multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary.

Methods: The case of a 30-years-old white female who developed multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary is presented.

Results: The patient had a disseminated disease and died 6 months after. The oncologic work-up, including physical examination, laboratory and radiographic study, fails to identify the primary site.

Conclusions: Intraocular involvement from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary has not yet reported. We describe this case together with a review of the literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Small Cell / diagnostic imaging
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / secondary*
  • Choroid Neoplasms / diagnostic imaging
  • Choroid Neoplasms / drug therapy
  • Choroid Neoplasms / secondary*
  • Fatal Outcome
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green
  • Neoplasms, Unknown Primary / diagnosis
  • Neoplasms, Unknown Primary / drug therapy
  • Neoplasms, Unknown Primary / pathology*
  • Ultrasonography

Substances

  • Indocyanine Green