Linezolid use associated with lactic acidosis

Scand J Infect Dis. 2005;37(2):153-4. doi: 10.1080/00365540410026022.

Abstract

Linezolid is a new synthetic antibiotic with a broad spectrum of activity against virtually all important Gram-positive infections. Lactic acidosis is a well known side-effect of metformin and nucleoside reverse-transcriptase inhibitors. We report a case in which lactic acidosis developed as an adverse effect of linezolid treatment.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / adverse effects*
  • Acidosis, Lactic / chemically induced*
  • Acidosis, Lactic / diagnosis*
  • Aged
  • Anti-Infective Agents / adverse effects*
  • Bacteremia / drug therapy*
  • Diagnosis, Differential
  • Humans
  • Linezolid
  • Lymphoma, T-Cell, Cutaneous*
  • Male
  • Methicillin Resistance
  • Oxazolidinones / adverse effects*
  • Staphylococcal Infections / drug therapy*

Substances

  • Acetamides
  • Anti-Infective Agents
  • Oxazolidinones
  • Linezolid