A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols

Adilah B Bahadoor; Alec Flyer; Glenn C Micalizio

doi:10.1021/ja050039+

A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols

J Am Chem Soc. 2005 Mar 23;127(11):3694-5. doi: 10.1021/ja050039+.

Authors

Adilah B Bahadoor¹, Alec Flyer, Glenn C Micalizio

Affiliation

¹ Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, USA.

PMID: 15771493
DOI: 10.1021/ja050039+

Abstract

A convergent two-step process is described for the synthesis of ene-1,5-diols that provides for union of two carbonyl electrophiles via a formal pentenyl dianion equivalent.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alcohols / chemical synthesis*
Aldehydes / chemistry*
Alkenes / chemical synthesis*
Alkynes / chemistry*
Ketones / chemistry*
Stereoisomerism

Substances

Alcohols
Aldehydes
Alkenes
Alkynes
Ketones