Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

Lancet Oncol. 2005 Apr;6(4):249-51. doi: 10.1016/S1470-2045(05)70097-8.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Benzamides
  • Drug Resistance, Neoplasm*
  • Gastrointestinal Stromal Tumors / drug therapy*
  • Gastrointestinal Stromal Tumors / genetics*
  • Humans
  • Imatinib Mesylate
  • Male
  • Middle Aged
  • Mutation
  • Neoplasm Metastasis
  • Piperazines / therapeutic use*
  • Proto-Oncogene Proteins c-kit / genetics*
  • Pyrimidines / therapeutic use*

Substances

  • Antineoplastic Agents
  • Benzamides
  • Piperazines
  • Pyrimidines
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit