Hormonal control of the IGF system in the sea bream ovary

Ann N Y Acad Sci. 2005 Apr:1040:320-2. doi: 10.1196/annals.1327.051.

Abstract

Numerous studies have described the presence of an intragonadal IGF system involved in regulation of gametogenesis in teleost fish. In the present study, the in vivo effects of estradiol-17beta (E2) and growth hormone (GH) exposure on IGF-I, IGF-II, IGF1R, and IGFBP2 gene expression in sea bream ovary were monitored by RT-PCR during prereproductive and reproductive periods. The evidence demonstrates that both hormones investigated here affect the ovarian IGF system, showing that it is not only under GH control, but also can be regulated by sexual hormones; this hormonal modulation is related to reproductive phase.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Female
  • Insulin-Like Growth Factor Binding Protein 2 / biosynthesis
  • Insulin-Like Growth Factor Binding Protein 2 / genetics
  • Insulin-Like Growth Factor Binding Protein 2 / physiology*
  • Insulin-Like Growth Factor I / biosynthesis
  • Insulin-Like Growth Factor I / genetics
  • Insulin-Like Growth Factor I / physiology
  • Insulin-Like Growth Factor II / biosynthesis
  • Insulin-Like Growth Factor II / genetics
  • Insulin-Like Growth Factor II / physiology
  • Ovary / metabolism
  • Ovary / physiology*
  • Receptor, IGF Type 1 / biosynthesis
  • Receptor, IGF Type 1 / genetics
  • Receptor, IGF Type 1 / physiology*
  • Sea Bream / genetics
  • Sea Bream / metabolism
  • Sea Bream / physiology*
  • Somatomedins / biosynthesis
  • Somatomedins / genetics
  • Somatomedins / physiology*

Substances

  • Insulin-Like Growth Factor Binding Protein 2
  • Somatomedins
  • Insulin-Like Growth Factor I
  • Insulin-Like Growth Factor II
  • Receptor, IGF Type 1