[Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome]

S Halioui-Louhaichi; O Azzabi; L Nefzi; M Ben Hariz; N Ben Mrad; B Ben Ammar; A Maherzi

doi:10.1016/j.arcped.2005.03.044

[Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome]

Arch Pediatr. 2005 Jul;12(7):1120-3. doi: 10.1016/j.arcped.2005.03.044.

[Article in French]

Authors

S Halioui-Louhaichi¹, O Azzabi, L Nefzi, M Ben Hariz, N Ben Mrad, B Ben Ammar, A Maherzi

Affiliation

¹ Service de pédiatrie, hôpital Mongi-Slim, La-Marsa, Tunisie. sonia.halioui@rns.tn

PMID: 15964528
DOI: 10.1016/j.arcped.2005.03.044

Abstract

Cushing's syndrome reveals McCune-Albright syndrome in a minority of patients. Bilateral adrenalectomy is performed on the majority of cases.

Case report: We present a case of McCune-Albright syndrome revealed by a Cushing's syndrome treated by metyrapone. Results were good, after a 4-year follow up.

Conclusion: Treatment with metyrapone could be recommended, for some patients, in McCune-Albright syndrome with Cushing's syndrome before chirurgical treatment.

Publication types

Case Reports
English Abstract

MeSH terms

Adrenal Hyperplasia, Congenital / complications
Adrenal Hyperplasia, Congenital / drug therapy
Cushing Syndrome / complications
Cushing Syndrome / drug therapy*
Enzyme Inhibitors / therapeutic use*
Female
Fibrous Dysplasia, Polyostotic / complications
Fibrous Dysplasia, Polyostotic / drug therapy*
Humans
Infant
Metyrapone / therapeutic use*
Treatment Outcome

Substances

Enzyme Inhibitors
Metyrapone