[Usefulness of adding antibiotic to cement in one stage exchange of chronic infection in total hip arthroplasty]

Med Clin (Barc). 2005 Jun 25;125(4):138-9. doi: 10.1157/13076942.
[Article in Spanish]

Abstract

Backgrounds and objective: Direct exchange using antibiotic-impregnated cement is a treatment option for hip prosthesis infection (HPI). Nevertheless, a local antibiotic use is not always possible. We present our experience with direct exchange with and without antibiotic-impregnated cement.

Patients and method: Fourteen patients with a HPI were treated with direct exchange. The femoral component was cemented with an antibiotic in 7 cases and in 7 it was not cemented. The patients received antibiotic prophylaxis and antibiotic treatment for a mean of 3 months. Clinical evolution of the infection was prospectively assessed.

Results: There were no differences with regard to the clinical and microbiologic characteristics between both groups. In the last control (minimum 2 years) all the patients were cured.

Conclusions: Our results suggest that direct exchange without local antibiotic is an option in HPI. Further studies are needed to evaluate the usefulness of antibiotic loaded cement.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents, Local / therapeutic use*
  • Antibiotic Prophylaxis / methods*
  • Arthroplasty, Replacement, Hip / methods*
  • Bacterial Infections / drug therapy*
  • Bacterial Infections / microbiology
  • Bone Cements / therapeutic use*
  • Chronic Disease
  • Female
  • Hip Prosthesis / microbiology*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Prosthesis-Related Infections / drug therapy*
  • Prosthesis-Related Infections / microbiology
  • Reoperation

Substances

  • Anti-Infective Agents, Local
  • Bone Cements