Abstract
HRMAS NMR of tau paired helical fragments assembled with heparin show an intensity decrease for those amino acids that are incorporated into the rigid core region, whereas the N-terminal amino acids maintain their full mobility.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alzheimer Disease / metabolism
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Intermediate Filaments / chemistry*
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Intermediate Filaments / metabolism
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Nuclear Magnetic Resonance, Biomolecular / methods*
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Protein Structure, Secondary
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Protein Structure, Tertiary
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tau Proteins / chemistry*
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tau Proteins / metabolism