Abstract
The thermal stability of virulent hepatitis E virus (HEV) and hepatitis A virus (HAV) was compared. Fecal suspensions of virus were heated to temperatures between 45 degrees C and 70 degrees C, and residual infectivity was determined in a cell culture system that was permissive for both viruses. Although HEV was less stable than was HAV, some HEV would most likely survive the internal temperatures of rare-cooked meat.
Publication types
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Comparative Study
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Research Support, N.I.H., Intramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cell Line
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Feces / virology
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Food Microbiology
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Hepatitis A / transmission
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Hepatitis A / virology
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Hepatitis A virus / growth & development*
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Hepatitis E / transmission
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Hepatitis E / virology
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Hepatitis E virus / physiology*
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Hot Temperature
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Humans
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Microscopy, Fluorescence