Ruthenium-catalyzed [2 + 2] cycloadditions of ynamides

Org Lett. 2005 Aug 18;7(17):3681-4. doi: 10.1021/ol0512841.

Abstract

Ruthenium-catalyzed [2 + 2] cycloadditions between norbornene and ynamides were investigated. The ynamide moiety was found to be compatible with the ruthenium-catalyzed cycloaddition conditions, giving the corresponding cyclobutene cycloadducts in moderate to good yields (up to 97%). [reaction: see text]