[Atypical ocular myasthenia gravis]

Rev Neurol (Paris). 2005 May;161(5):543-8. doi: 10.1016/s0035-3787(05)85088-x.
[Article in French]

Abstract

The diagnosis of ocular myasthenia gravis is rarely in doubt in patients with a proper history and typical clinical findings. However, myasthenia gravis can mimick any pupil-sparing eye movement disorder and several diseases may masquerade myasthenia gravis. We review the atypical presentations and differential diagnoses in ocular myasthenia gravis, describing four patients with some of these conditions (4th nerve palsy, near spasm reflex, one-and-a-half syndrome, orbital meningioma). The correct interpretation of the clinical findings associated with appropriate neuro-imaging studies allowed the appropriate diagnosis in these cases.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Diplopia / diagnosis
  • Diplopia / etiology
  • Eye Diseases / diagnosis
  • Eye Diseases / etiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meningioma / complications
  • Meningioma / diagnosis
  • Middle Aged
  • Myasthenia Gravis / complications*
  • Myasthenia Gravis / diagnosis
  • Neurologic Examination
  • Oculomotor Nerve Diseases / diagnosis
  • Oculomotor Nerve Diseases / physiopathology
  • Orbital Neoplasms / complications
  • Orbital Neoplasms / diagnosis
  • Trochlear Nerve Diseases / diagnosis