Cervicofacial actinomycosis: still a difficult differential diagnosis

Acta Otorhinolaryngol Ital. 2005 Apr;25(2):116-9.

Abstract

Cervicofacial actinomycosis, a rare chronic infectious disease, is, however, an important clinical entity, due to the difficulties involved, still today, in its diagnosis. Following personal experience in a case referred to our Department, and in agreement with reports in the literature, attention is drawn to the presenting clinical manifestations, stressing that these are often confusing since they mimic those of other diseases, Moreover, many pre-operative investigations (radiological scans, incisional biopsy, fine-needle aspiration) are generally nonspecific. Finally, surgical excision of the mass is now the last essential step to make a definitive diagnosis and define the appropriate antibiotic therapy.

L’actinomicosi cervicofacciale è una rara malattia infettiva cronica che rappresenta tuttavia un’importante entità clinica, a causa delle difficoltà che ancora pone in fase diagnostica. Basandoci sull’osservazione di un caso clinico occorso nel nostro Reparto, in accordo con la letteratura, abbiamo sottolineato come le manifestazioni cliniche d’esordio siano spesso confondenti, poiché comuni ad altri processi patologici, e come le indagini pre-operatorie (scansioni radiologiche, biopsie escissionali, agoaspirato) risultino in genere non specifiche. L’escissione chirurgica della massa è quindi attualmente ancora essenziale per porre diagnosi certa ed istituire l’appropriata terapia antibiotica.

Publication types

  • Case Reports

MeSH terms

  • Actinomycosis, Cervicofacial / drug therapy
  • Actinomycosis, Cervicofacial / pathology*
  • Actinomycosis, Cervicofacial / surgery
  • Chronic Disease
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Neutrophils / metabolism
  • Penicillins / therapeutic use

Substances

  • Penicillins