Although morselized cancellous autograft or allograft has been shown to be highly successful for management of smaller cavitary defects in revision TKA, structural allografts often are required for large, contained, or uncontained osseous defects. Early clinical results of revision TKA using structural allografts have been encouraging with high allograft-host union rates, as long as adequate fixation is obtained. The use of intramedullary stems with sufficient length to engage diaphyseal bone is recommended to lessen load transmission to the structural allograft and to reduce the risk of late allograft collapse or fracture. Extensive preoperative planning, meticulous operative technique, and an extended period of postoperative rehabilitation are required for optimal