Comparison of target concentration intervention strategy with conventional dosing of digoxin

Indian Heart J. 2005 May-Jun;57(3):265-7.

Abstract

Digoxin is a widely used drug in patients with congestive heart failure. The present study compared the quality of life of congestive heart failure patients on one year follow-up period with two different dosing of digoxin (5/7 therapy and 7/7 therapy in whom the target serum digoxin concentration is maintained). Quality of life significantly improved in intervention group thus emphasizing the need for continuous dosing of digoxin based on target concentration.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Cardiotonic Agents / blood
  • Cardiotonic Agents / therapeutic use
  • Case-Control Studies
  • Digoxin / blood*
  • Digoxin / therapeutic use*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Heart Failure / diagnosis
  • Heart Failure / drug therapy*
  • Heart Function Tests
  • Humans
  • Male
  • Prospective Studies
  • Reference Values
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Cardiotonic Agents
  • Digoxin