Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+

Antimicrob Agents Chemother. 2005 Nov;49(11):4807-8. doi: 10.1128/AAC.49.11.4807-4808.2005.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / physiology*
  • Animals
  • Antimalarials / pharmacology*
  • Calcium / metabolism*
  • Chloroquine / pharmacology*
  • Membrane Proteins / genetics
  • Membrane Proteins / physiology*
  • Membrane Transport Proteins
  • Mutation*
  • Plasmodium falciparum / drug effects*
  • Plasmodium falciparum / genetics
  • Protozoan Proteins / genetics
  • Protozoan Proteins / physiology*
  • Vacuoles / metabolism*

Substances

  • ATP-Binding Cassette Transporters
  • Antimalarials
  • Membrane Proteins
  • Membrane Transport Proteins
  • PfCRT protein, Plasmodium falciparum
  • Protozoan Proteins
  • mdr gene protein, Plasmodium
  • Chloroquine
  • Calcium