Fibrinogen, homocyst(e)ine, and C-reactive protein concentrations relative to sex and socioeconomic status in British young people

Am J Hum Biol. 2005 Nov-Dec;17(6):809-13. doi: 10.1002/ajhb.20447.

Abstract

This study assesses the prevalence of recently identified coronary heart disease (CHD) risk factors in young people of differing socioeconomic status (SES). From November 2001 through March 2002, 100 boys and 108 girls, of age 12.9 +/- 0.3 years, selected from differing SES were assessed for CHD risk factors. Measurements included fibrinogen (Fg), homocyst(e)ine (Hcy), and C-reactive protein (CRP). Fibrinogen was significantly greater among boys from a higher SES compared with those from a low SES (P < or = 0.05). Differences according to sex (P < or = 0.05) were identified for Fg and CRP. The data indicate the prevalence of recently identified CHD risk factors in this cohort of British schoolchildren. For the purpose of this article, the phrase "young people" embraces both children and adolescents.

Publication types

  • Comparative Study

MeSH terms

  • Biomarkers / blood
  • C-Reactive Protein / metabolism*
  • Child
  • Coronary Disease / blood
  • Coronary Disease / epidemiology
  • Female
  • Fibrinogen / metabolism*
  • Follow-Up Studies
  • Homocysteine / blood*
  • Humans
  • Immunoassay
  • Male
  • Nephelometry and Turbidimetry
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Social Class*
  • Socioeconomic Factors
  • United Kingdom / epidemiology

Substances

  • Biomarkers
  • Homocysteine
  • Fibrinogen
  • C-Reactive Protein