Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center

J Clin Microbiol. 2005 Dec;43(12):6120-2. doi: 10.1128/JCM.43.12.6120-6122.2005.

Abstract

Aspergillus isolates (n = 103) collected from cancer patients were screened to determine the taxonomic distribution and quantity of gliotoxin production. Gliotoxin was detected in 93% of Aspergillus fumigatus, 75% of A. niger, 25% of A. terreus, and 4% of A. flavus cultures. Gliotoxin concentrations were highest in cultures of A. fumigatus.

MeSH terms

  • Aspergillosis / epidemiology*
  • Aspergillosis / microbiology*
  • Aspergillus / classification*
  • Aspergillus / growth & development
  • Aspergillus / isolation & purification*
  • Culture Media
  • Gliotoxin / biosynthesis*
  • Humans
  • Neoplasms / complications*
  • Species Specificity

Substances

  • Culture Media
  • Gliotoxin