Yellow teeth, seizures, and mental retardation: a less severe case of Kohlschütter-Tönz syndrome

Am J Med Genet A. 2006 Feb 1;140(3):281-3. doi: 10.1002/ajmg.a.31071.

Abstract

We describe an 11-year-old boy with hypoplastic amelogenesis imperfecta, yellow teeth, seizures, and developmental delay, which are the hallmarks of Kohlschütter-Tönz syndrome. Compared to other reported cases of the syndrome, our patient had less severe developmental delay. Also, spasticity and loss of mental capacity should not be considered obligatory manifestations of the syndrome because they are not present in half of reported patients, as well as in our family. Origin of the parents of our patient from neighboring villages supports autosomal recessive inheritance of Kohlschütter-Tönz syndrome.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / genetics
  • Abnormalities, Multiple / pathology*
  • Amelogenesis Imperfecta / pathology
  • Child
  • Developmental Disabilities / pathology
  • Humans
  • Intellectual Disability / pathology*
  • Karyotyping
  • Male
  • Seizures / pathology*
  • Syndrome
  • Tooth Abnormalities*