Oral health related quality of life is affected by disease activity in Behçet's disease

Oral Dis. 2006 Mar;12(2):145-51. doi: 10.1111/j.1601-0825.2005.01173.x.

Abstract

Objectives: This study aimed to investigate oral and general health related quality of life (QoL) in patients with Behçet's Disease (BD) and to assess the performance of Turkish versions of oral health related quality questionnaires.

Subjects and methods: Ninety-four BD patients, 24 patients with recurrent aphthous stomatitis (RAS), 113 healthy controls (HC) and 44 dental patients were investigated. QoL was assessed by oral health impact profile-14 (OHIP-14), oral health related quality of life (OHQoL) and short form-36 (SF-36) questionnaires.

Results: OHQoL, OHIP-14 and SF-36 subscale scores were significantly worse in patients with BD compared with those in HC (P < 0.05). Both OHIP-14 and OHQoL scores were significantly worse in active patients compared with inactives in BD and RAS (P < 0.05). Scores of SF-36 Role physical, Role emotional and Vitality were also lower in active patients than in inactives in BD (P < 0.05). Scores of OHIP-14 and OHQoL were significantly worse in patients treated with colchicine compared with those treated with immunosuppressives (P < 0.05).

Conclusions: Both oral and general QoL was impaired in BD and associated with disease activity and treatment modalities. Translated Turkish versions of OHIP-14 and OHQoL were also observed to be valid and reliable questionnaires for further studies.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Attitude to Health
  • Behcet Syndrome / drug therapy
  • Behcet Syndrome / physiopathology
  • Behcet Syndrome / psychology*
  • Colchicine / therapeutic use
  • Cross-Sectional Studies
  • Emotions
  • Female
  • Health Status
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Oral Health*
  • Quality of Life*
  • Reproducibility of Results
  • Stomatitis, Aphthous / drug therapy
  • Stomatitis, Aphthous / physiopathology
  • Stomatitis, Aphthous / psychology
  • Surveys and Questionnaires / standards

Substances

  • Immunosuppressive Agents
  • Colchicine