Double functionalization of carbon nanotubes for multimodal drug delivery

Chem Commun (Camb). 2006 Mar 21:(11):1182-4. doi: 10.1039/b516309a. Epub 2006 Feb 13.

Abstract

Multi-walled carbon nanotubes have been covalently functionalized via 1,3-dipolar cycloaddition of azomethine ylides with orthogonally protected amino functions that can be selectively deprotected and subsequently modified with drugs and fluorescent probes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry*
  • Cyclization
  • Drug Carriers / chemistry*
  • Microscopy, Scanning Tunneling
  • Nanotubes, Carbon / chemistry*
  • Pharmaceutical Preparations / administration & dosage*
  • Solubility

Substances

  • Azo Compounds
  • Drug Carriers
  • Nanotubes, Carbon
  • Pharmaceutical Preparations