Oxone as an inexpensive, safe, and environmentally benign oxidant for C-H bond oxygenation

Org Lett. 2006 Mar 16;8(6):1141-4. doi: 10.1021/ol0530272.

Abstract

[reaction: see text] This paper describes the application of peroxide-based oxidants in the Pd(OAc)(2)-catalyzed acetoxylation and etherification of arene and alkane C-H bonds. Oxone in acetic acid and/or methanol proved particularly effective, and these transformations were applied to a wide variety of substrates.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Combinatorial Chemistry Techniques*
  • Indicators and Reagents
  • Molecular Structure
  • Oxidants / chemistry*
  • Oxidants / economics
  • Peroxides / chemistry*
  • Sulfuric Acids / chemistry*
  • Sulfuric Acids / economics

Substances

  • Indicators and Reagents
  • Oxidants
  • Peroxides
  • Sulfuric Acids
  • potassium peroxymonosulfuric acid