Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice

Cell Death Differ. 2006 Jun;13(6):902-8. doi: 10.1038/sj.cdd.4401902.

Authors

T M Johnson¹, L D Attardi

Affiliation

¹ Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University Medical School, Stanford, CA, USA.

PMID: 16557272
DOI: 10.1038/sj.cdd.4401902

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Aging, Premature / genetics
Aging, Premature / metabolism
Animals
Apoptosis / genetics
Cell Cycle / genetics
Cell Transformation, Neoplastic / genetics
Cell Transformation, Neoplastic / metabolism*
Cell Transformation, Neoplastic / pathology
Genomic Instability
Mice
Mice, Knockout
Mutation
Neoplasms / genetics
Neoplasms / metabolism*
Neoplasms / pathology
Phosphorylation
Protein Processing, Post-Translational*
Signal Transduction
Tumor Suppressor Protein p53 / genetics
Tumor Suppressor Protein p53 / metabolism*

Substances

Tumor Suppressor Protein p53