Genital anaesthesia persisting six years after sertraline discontinuation

J Sex Marital Ther. 2006 Jul-Sep;32(4):327-30. doi: 10.1080/00926230600666410.

Abstract

Sexual side-effects, in general, are common with selective serotonin-reuptake inhibitors (SSRIs). Genital anaesthesia is a rare side-effect previously described with sertraline and fluoxetine use. With SSRI discontinuation, the sexual side-effects are expected to resolve. We report a case of a 26-year-old male who experienced genital anaesthesia during sertraline treatment and continued to be symptomatic despite medication discontinuation 6 years previously. To date, there have been no published reports of SSRI-induced sexual side-effects persisting beyond SSRI discontinuation. This case highlights the complex interplay of psychopharmacologic and psychodynamic factors that can occur in patients with sexual dysfunction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Depression / drug therapy
  • Humans
  • Hypesthesia / chemically induced*
  • Male
  • Selective Serotonin Reuptake Inhibitors / administration & dosage
  • Selective Serotonin Reuptake Inhibitors / adverse effects*
  • Sexual Dysfunction, Physiological / chemically induced*

Substances

  • Serotonin Uptake Inhibitors