Placental malaria and immunity to infant measles

Arch Dis Child. 2006 Jun;91(6):507-8. doi: 10.1136/adc.2005.085274.

Abstract

The efficiency of transplacental transfer of measles specific antibody was assessed in relation to placental malaria. Infection at delivery was associated with a 30% decrease in expected cord measles antibody titres. Uninfected women who received anti-malarial drugs during pregnancy transmitted 30% more antibody than those who received no antimalarial drugs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies / blood*
  • Antimalarials / therapeutic use
  • Female
  • Ghana
  • Humans
  • Immunity, Maternally-Acquired*
  • Immunoglobulin G / blood
  • Infant
  • Infant, Newborn
  • Malaria / drug therapy
  • Malaria / immunology*
  • Male
  • Measles / immunology*
  • Multivariate Analysis
  • Placenta Diseases / drug therapy
  • Placenta Diseases / immunology*
  • Placental Circulation
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / immunology*

Substances

  • Antibodies
  • Antimalarials
  • Immunoglobulin G