Nasal extranodal NK/T-cell lymphoma presenting as a perforating palatal ulcer: a diagnostic challenge

Indian J Dermatol Venereol Leprol. 2006 May-Jun;72(3):218-21. doi: 10.4103/0378-6323.25784.

Abstract

A 40-year-old man presented with chronic nasal stuffiness and bloodstained discharge of 3 years' duration, along with a non-healing palatal ulcer since 2 months. Examination revealed a perforation in the midline on the hard palate and a superficial ulcer on the soft palate. Histopathology and immunohistochemistry suggested a diagnosis of extranodal nasal/nasal-type T-cell lymphoma. The patient was started on multiagent chemotherapy in the form of cyclophosphamide, doxorubicin, vincristine and prednisolone but succumbed after two cycles. Only one case of nasal T cell lymphoma presenting as nasal septal perforation, oronasal fistula and a concomitant palatal ulcer has been described. We report this case of a perforating palatal ulcer as a rare presentation of nasal lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Fatal Outcome
  • Humans
  • Killer Cells, Natural / pathology
  • Lymphoma, T-Cell / diagnosis*
  • Lymphoma, T-Cell / drug therapy
  • Lymphoma, T-Cell / pathology*
  • Male
  • Mouth Diseases / diagnosis
  • Mouth Diseases / pathology*
  • Mouth Neoplasms / diagnosis
  • Mouth Neoplasms / pathology
  • Nose Neoplasms / diagnosis*
  • Nose Neoplasms / drug therapy
  • Nose Neoplasms / pathology
  • Oral Ulcer / pathology*