Cognitive profile of neurofibromatosis type 1

Semin Pediatr Neurol. 2006 Mar;13(1):8-20. doi: 10.1016/j.spen.2006.01.006.

Abstract

General consensus has yet to be reached with regard to the exact cognitive profile of children with neurofibromatosis type 1 (NF1). The current overview seeks to provide a more comprehensive review of the literature by examining studies that have specifically compared individuals with NF1 to siblings, controls, and/or norms. We also examined results of studies that compared individuals with NF1 with various manifestations to each other. Consistent with previous reviews, no clear cognitive profile emerged; however, greater insight into patterns was obtained. Additionally, future directions for research on NF1 were suggested.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cognition / physiology*
  • Cognition Disorders / etiology*
  • Humans
  • Intelligence / physiology
  • Language Disorders / etiology
  • Nervous System Diseases
  • Neurofibromatosis 1 / complications*
  • Neurofibromatosis 1 / physiopathology*
  • Neuropsychological Tests / statistics & numerical data
  • Perceptual Disorders / etiology