Adverse outcome in women with thrombophilia and bilateral uterine artery notches

Elvira Grandone; Donatella Colaizzo; Pasquale Martinelli; Dario Paladini; Giovanni di Minno; Maurizio Margaglione

doi:10.1016/j.fertnstert.2006.01.038

Adverse outcome in women with thrombophilia and bilateral uterine artery notches

Fertil Steril. 2006 Sep;86(3):726-7. doi: 10.1016/j.fertnstert.2006.01.038. Epub 2006 Jul 7.

Authors

Elvira Grandone¹, Donatella Colaizzo, Pasquale Martinelli, Dario Paladini, Giovanni di Minno, Maurizio Margaglione

Affiliation

¹ IRCCS Casa Sollievo della Sofferenza, S. Giovanni R. (FOGGIA), Foggia, Italy. e.grandone@operapadrepio.it

PMID: 16828480
DOI: 10.1016/j.fertnstert.2006.01.038

Abstract

Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher risk to have an adverse outcome than women without.

Publication types

Controlled Clinical Trial

MeSH terms

Adult
Congenital Abnormalities / epidemiology*
Female
Humans
Incidence
Italy / epidemiology
Pregnancy
Pregnancy Complications, Cardiovascular / epidemiology*
Pregnancy Outcome / epidemiology*
Prospective Studies
Risk Assessment / methods*
Risk Factors
Thrombophilia / epidemiology*
Uterus / blood supply*