Abstract
Herein we describe a small-molecule, non-peptidic, inhibitor for botulinum neurotoxin A protease, that displays for the first time efficacy in a cell-based assay.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Biological Assay
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Botulinum Toxins, Type A / antagonists & inhibitors*
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Mice
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Neuroblastoma / enzymology*
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Neuroblastoma / pathology
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Neurotoxins / antagonists & inhibitors*
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Protease Inhibitors / pharmacology*
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Tumor Cells, Cultured
Substances
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Neurotoxins
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Protease Inhibitors
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Botulinum Toxins, Type A