Extravasation of propofol is associated with tissue necrosis in small children

Paediatr Anaesth. 2006 Aug;16(8):887-9. doi: 10.1111/j.1460-9592.2006.01873.x.

Abstract

Propofol is widely used for induction of anesthesia and many reports document extravasation and even intra-arterial injections without clinical sequelae. We report a case of tissue necrosis after subcutaneous injection of propofol in a 31-day-old infant.

Publication types

  • Case Reports

MeSH terms

  • Ambulatory Surgical Procedures
  • Anesthetics, Intravenous / adverse effects*
  • Extravasation of Diagnostic and Therapeutic Materials / complications*
  • Female
  • Forefoot, Human / pathology*
  • Humans
  • Infant
  • Injections, Intravenous
  • Necrosis / chemically induced
  • Propofol / adverse effects*

Substances

  • Anesthetics, Intravenous
  • Propofol